p75 NGF Receptor Polyclonal Antibody, Cy3 Conjugated - 100 µL

Alternate_names :p75 Description :Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glu cose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the supra chiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver. Applications :WB | IHC-P | IHC | ICC Species_reactivity :Human, Mouse, Rat, Others Clonality :Polyclonal Storage_Buffer :Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Concentration :1ug/ul